Effect of extract from Trichosathis Fructus, Carthami Flos, Chuanxiong Rhizoma, and Chrysanthemi Flos on oxidative stress-induced gut immunity in Drosophila melanogaster
Why this work is in the frame
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Bibliographic record
Abstract
Objective To study the effect of the extract from Chinese materia medica(CMM) on oxidative stress-induced gut immunity of Drosophila melanogaster. Methods D. melanogaster was treated by Paraquat and H2O2 with or without CMM, and the effects of 50 kinds of CMM on the survival rate of D. melanogaster in response to oxidative stress were recorded. And the antioxidant effects of CMM on lifespan and the number of ISC and enteroblast(EB) in intestinal epithelium cells were analyzed. Results The extracts from Trichosanthes kirilowii(Trichosathis Fructus), Carthamus tinctorius(Carthami Flos), Ligusticum chuanxiong(Chuanxiong Rhizoma), and Chrysanthemum monfolium(Chrysanthemi Flos) could significantly improve the survival rate of Paraquat and H2O2-induced D. melanogaster, increase the lifespan of D. melanogaster, and regulate Paraquat-induced and age-related changes in the number of ISC and EB. Conclusion The extracts from T. kirilowii, C. tinctorius, L. chuanxiong, and C. monfolium could significantly improve the oxidative stress-induced gut immunity of D. melanogaster.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it