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Record W2376930652

Determination of Related Substances in Suxamethonium Chloride Injection

2009· article· en· W2376930652 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPlant-based Medicinal Research
Canadian institutionsCAE (Canada)
Fundersnot available
KeywordsChemistryChlorideChromatographyCholine chlorideHydrolysisTitrationDetection limitCholineOrganic chemistryBiochemistry
DOInot available

Abstract

fetched live from OpenAlex

Aim To establish a method for quality control of related substances in suxamethonium chloride injection.Methods Choline choride in the injection was determined by thin-layer chromatography(TLC),and hydrolysis products in the injection by titration.Results Choline choride and other related substances in the injection were separated by TLC.The lowest detectable limit of choline choride was 0.2μg.The limit of choline choride exceeded 3.0% in the suxamethonium chloride reference substance,one batch of suxamethonium chloride raw material,and three batchs of suxamethonium chloride injection.Hydrolysis products in three batchs of suxamethonium chloride injection were below 3.0%.Conclution This method is simple and fast,which can be used to control related substances in suxamethonium chloride injection。

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.488
Threshold uncertainty score0.522

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.125
GPT teacher head0.484
Teacher spread0.358 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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