Relationship between Cognition of Obstructive Sleep Apnea/Hypopnea Syndrome Patients and Insulin-like Growth Factor II
Bibliographic record
Abstract
Objective To determine the relationship of blood serum insulin like growth factor Ⅱ(IGF-Ⅱ)concentration with deterioration of cognitive function in patients with OSAHS and to explore the possible mechanism of cognitive impairment of OSAHS.Methods Twenty-eight male patients with OSAHS and fourteen normal men enrolled in the study.Polysomnography and MoCA had been conducted.Blood serum IGF-Ⅱ concentration was measured with ELISA.Results The blood serum IGF-Ⅱ concentration of OSAHS group was significantly increased compared with control group(t=5.587,P=0.000).The blood serum IGF-Ⅱ concentration of subjects was significantly negative associated with the score of MoCA(r=-0.483,P=0.001).It was significantly positive correlated with AHI and S1+S2(AHI:r=0.483,P=0.001,S1+S2:r=0.549,P=0.000),and it was significantly negative associated with the LSO,S3+S4 and REM(LSO:r=-0.449,P=0.003,S3+S4:r=-0.612,P=0.000,REM:r=-0.395,P=0.010).Conclusion The blood serum IGF-Ⅱ concentration of OSAHS is significantly increased compared with healthy people.It possibly plays a role in the mechanism of cognitive impairment of OSAHS.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".