Inhibitions of lipid peroxidation and protection of DNA damage by triterpenoids from labiatae Isodon
Bibliographic record
Abstract
The antioxidative effects of seven triterpenoids separated from labiatae Isodon were examined by testing their protection against DNA damage in human peripheral blood mononuclear cells induced by H2O2,inhibition of lipid peroxidation and DNA strand breakage.These triterpenoids exerted variably protective effects in these systems.Ursolic acid has the strongest protective effects in all three systems.2α,3β,dihydroxy-urs-12-en-28-oid acid are effective in inhibiting lipid peroxidatian but weak in protection DNA strand breakage.It's isomer 2α,3α,23-trihydroxy-urs-12-en-28-oic-acid showed opposite actions.Oleanolic acid is only effective in DNA damage induced by H2O2 in single cell.The relationship between antioxidations and structures are also discussed.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".