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Record W2383690840

Expression of Porcine Phospholipase A2 Gene in Aspergillus niger

2014· article· en· W2383690840 on OpenAlexaff
Deng Chen-x

Bibliographic record

VenueBiotechnology(Faisalabad) · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEnzyme Production and Characterization
Canadian institutionsScience North
Fundersnot available
KeywordsSignal peptideAspergillus nigerExtracellularHomologous recombinationPhospholipase A2IntracellularPeptideRecombinant DNABiochemistryEnzymeMolecular biologyPhospholipaseBiologyHeterologous expressionHeterologousGeneChemistry
DOInot available

Abstract

fetched live from OpenAlex

Objective:The purpose was to express porcine phospholipase gene(PLA2,PLA2M) in Aspergillus niger.Method:The study constructed porcine phospholipase A2 recombinant expression vector pSZHG-PLA2,pSZHGS-PLA2M,which contained its own signal peptide or glucoamylase signal peptide.pSZHG-PLA2 and pSZHGS-PLA2M were transformed into Aspergillus niger by Agrobacterrium-tumefacien mediated method.Result:After screened,respectively,both pSZHG-PLA2 and pSZHGS-PLA2M obtained a homologous recombination transformant.To screen out homologous recombination strains for fermentation,respectively,detected the intracellular enzyme activity and extracellular enzyme activity.The result showed that the intracellular and extracellular enzyme activity of homologous recombination strain,which guided by its signal peptide,were 21.68U/mL and 2.12 U/mL.The intracellular and extracellular enzyme activity of homologous recombination strain,which guided by glucoamylase signal peptide,were 15.07U/mL and 3.10 U/mL.Conclusion:The results showed that the study used of its signal peptide and glucoamylase signal peptide had failed to obtain effective secretion of the recombination porcine phospholipase A2 gene in Aspergillus niger.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.031
Threshold uncertainty score0.597

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.219
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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