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Record W2384652208

Sensitivity of BmHc Cell Line From Bombyx mori to Lipopolysaccharide and 20-hydroxyecdysone

2007· article· en· W2384652208 on OpenAlexaff
Wen Li

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldImmunology and Microbiology
TopicInvertebrate Immune Response Mechanisms
Canadian institutionsCAE (Canada)
Fundersnot available
KeywordsBombyx moriCell cultureCell biologyChemistryIntracellularCellCell growthLipopolysaccharideTransduction (biophysics)Confocal microscopyMolecular biologyCell membraneBiologyBiochemistryGeneImmunology
DOInot available

Abstract

fetched live from OpenAlex

To study signal transduction path way in intracellular cells of insect and express foreign gene in cultured hemocytes,a BmHc hemocytes cell line from B.mori was established in TC-199 medium.The BmHc cell line consists of all types of hemocytes including prohemocytes,spherulocytes,granulocytes and plasmatocytes,etc.Doubling time of the cell line is about 30 h.LPS elicited hemocytes to synthesize antibacterial proteins and peptides and prompted cells to uptake more Ca2+ to take part in active cell proliferation.Flu-3 AM study with TCS-SP2 laser scanning confocal microscope showed that Ca2+ distributed on the membrane of prohemocytes and granulocytes,but some of them were on the signal path way to the prohemocytes nuclei in 30 min after LPS induction;while under the same condition,the membrane of the cells was only slightly stained with Flu-3 AM after treatment with 20E.LPS elicited and opened Ca2+ channel and caused the change of.A relatively stable change of in the cells when 20E was added to the culture medium that indicated 20E is not an effective enhancer for sensitive Ca2+ channel on the cell membrane.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.024
Threshold uncertainty score0.926

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.228
Teacher spread0.219 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes1
Has abstractyes

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Same topicInvertebrate Immune Response MechanismsFrench-language works237,207