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Record W2386426230

Functional MRI for changed brain default mode network in ischemic stroke patients

2015· article· en· W2386426230 on OpenAlexaboutno aff
Che Zhang

Bibliographic record

VenueZhonghua laonian xin-nao-xueguanbing zazhi · 2015
Typearticle
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsnot available
Fundersnot available
KeywordsDefault mode networkPosterior cingulatePrecuneusMedicineMontreal Cognitive AssessmentStroke (engine)Prefrontal cortexCardiologyInternal medicineAnterior cingulate cortexFunctional magnetic resonance imagingNeuroscienceCognitionPsychologyCognitive impairmentPsychiatryRadiology
DOInot available

Abstract

fetched live from OpenAlex

Objective To study the changed brain default mode network in chronic ischemic stroke patients by functional MRI.Methods Seventeen chronic ischemic stroke patients served as an ischemic stroke group and 22sex-and age-matched healthy subjects undergoing physical examination served as a control group in this study.Their functional MRI data and Montreal congnitive assessment(MoCA)and Mini-Mental State Examination(MMSE)scores were recorded.Default mode network was taken from the ventromedial prefrontal cortex,right posterior cingulate cortex and left posterior cingulate cortex to generate the default mode network mask.Voxel functional connectivity in the default mode network mask was calculated.Association of functional connectivity strength with MoCA and MMSE scores and infarction size were analyzed by Pearson correlation analysis.Results The functional connectivity of medial prefrontal cortex(MPFC)and posterior cingulate cortex/precuneus was significantly lower in ischemic stroke group than in control group(P0.05).The functional connectivity of MPFC in ischemic stroke group was positively associated with the MoCA score(r=0.619,P=0.008).Conclusion Default mode network is damaged before cognitive impairment following ischemic stroke,which is the initial factor for cognitive impairment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.278
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractyes

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