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Record W2387580049

Clinical value of magnetic resonance imaging graded by SPARCC and HLA-B27 in diagnosing early ankylosing spondylitis

2012· article· en· W2387580049 on OpenAlexaboutno aff
Chen Xiao-fe

Bibliographic record

VenueChinese Journal of Clinical Research · 2012
Typearticle
Languageen
FieldMedicine
TopicSpondyloarthritis Studies and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsAnkylosing spondylitisMedicineBASDAIMagnetic resonance imagingNuclear medicineSpondylitisRadiologyInternal medicineDisease
DOInot available

Abstract

fetched live from OpenAlex

Objective To study the clinical value of magnetic resonance imaging(MRI) in low fields on sacroiliac joints(SIJs) and human leukocyte antigen(HLA)-B27 in diagnosing early ankylosing spondylitis(AS). Methods Forty patients with AS corresponding to the modified New York criteria were included.The HLA-B27 was measured,and MRI in low fields on SIJs was examined in all patients.The results of MRI were scored according to the spondyloarthritis research consortium of Canada(SPARCC),and the correlative analysis between SPARCC score of MRI and Bath AS disease activity index(BASDAI) score in clinic was performed. Results The positive and negative expressions of HLA-B27 were 35 cases(87.5%) and 5 cases(12.5%),respectively.There was no significant difference in SPARCC score between HLA-B27 negative group(18.30±9.78)and positive group(12.40±4.86)(t=1.709,P=0.105).The SPARCC score in active period was higher than that in quiescent period(17.14±3.80 vs 5.58±2.40,t=8.521,P=0.000).Pearson correlative analysis showed that SPARCC score was positively correlated to the BASDAI score(r=0.675,P0.05),and demonstrated that there was a better correlation in two score systems. Conclusions SPARCC score of MRI on SIJs could provide important evidence for diagnosing the early AS.HLA-B27 detection must rely on imaging condition as foundation in order to display its effect.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.108
GPT teacher head0.502
Teacher spread0.394 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2012
Admission routes1
Has abstractyes

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