Effect of Carotid Atherosclerosis on Lacunar Infarction,Leukoencephalopathy and Cognition Disorders in Elderly Hypertension Patients
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Bibliographic record
Abstract
Objective To investigate the relationship of carotid atherosclerosis(CA) with lacunar infarction(LI),leukoencephalopathy(LE) and cognition disorders in elderly hypertension patients.Methods A total of 64 elderly hypertension patients hospitalized in this hospital from October 2010 to December 2012 were divided,according to properties of carotid plaque,into groups A(with stable plaque,n = 27),B(with unstable plaque,n = 37);another 38 healthy elderly subjects without CA were enrolled as control group.Blood fat,blood pressure were detected,carotid ultrasound and brain CT scan carried out,cognitive function determined by Montreal Cognitive Assessment scale(MoCA scale).Results LDL level was higher in group B than in group A,HDL lower,SBP higher in group B than in control group(P 0.05).There was no significant difference in IMT of common carotid artery and internal carotid artery in 3 groups(P 0.05).The incidences of T2DM,LE and cognitive function were higher in group B than in groups A,control,and LI incidence lower than in group A,but higher than in control group(P 0.05).The incidences of T2DM,LI,LE,cognition disorders were higher in group A than in group control(P 0.05).The scores of visuospatial,executive ability,delayed recall in MoCA scale were lower in group B than in groups A,control(P 0.05).By results of linear correlation analysis,the detection rate of unstable plaque was positively correlated with incidence of LE(r = 0.187,P 0.05),negatively with HDL level(r =-0.536,P = 0.033),not linearly correlated with incidences of LI and cognition disorders(P 0.05).Conclusion The incidences of LI,LE,cognition disorders are higher in elderly patients with hypertension combined with unstable carotid plaque,and dyslipidemia is an important factor leading to CA.Lipid-lowering therapy and dietary intervention should be given when treating elderly hypertension patients.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it