Effects of polyglucose solution on erythrocyte rheological changes after cardiopulmonary resuscitation in experimental dogs
Bibliographic record
Abstract
Objective To investigate the effects of polyglucose solution on red blood cell rheological parameters after cardiopulmonary resuscitation in experimental dogs Methods Sixteen healthy mongrel dogs, weighting 11-20 kg, 1-2 years old, were divided randomly into 2 groups: control group (infusion of only Ringer's solution after cardiopulmonary resuscitation), trial group (quick infusion of polyglucose solution after cardiopulmonary resuscitation) Endotracheal intubation and mechanical ventilation after anesthetization with 3% barbiturate natrium (0 5-1 0 ml/kg) and vecuronium bromide (0 2 mg/kg), fentanyl and vecuronium bromide were used to maintain the anesthesia Two poles were emplaced in skin of right chest and left heart of these dogs Alternating current (50-80 V) stimulation of the dogs caused appearance of ventricular fibrillation (VF) and blood circulation arrest, and at the same time, ventilation was stopped Eight minutes later, mechanical ventilation and cardiopulmonary resuscitation (CPR) were resumed at the same time, and followed by routine support therapy after success of CPR Blood samples were collected via the femoral vein at 5 min before and after cardiac arrest (CA), at 30, 60, 90, and 120 min after CPR for the detection of RBC aggregation index (RAI), RBC deformation index (RDI), RBC rigidity index (RRI), high shear blood viscosity (HBV), low shear blood viscosity (LBV), Casson yield stress (CYS), and Casson viscosity (CV) Statistical analysis SPSS11 0 for windows was used to perform the Independent T Test and Paired samples T Test Results There were significant changes in RAI, RDI, RRI, LBV, and CYS in the control group ( P 0 05), but no significant change in HBV and CV was found before and after CPR ( P 0 05) No significant difference in parameters in the experimental group was found before and after CPR ( P 0 05) RAI at 90 and 120 min after CPR ( P 0 05), RDI at 60, 90, and 120 min after CPR ( P 0 05), RRI at 30, 60, 90, and 120 min after CPR ( P 0 01), LBV and CYS at 90 min after CPR ( P 0 05) and at 120 min after CPR ( P 0 01) in the two groups were significantly different Conclusion After CPR in non hemorrhagic CA, quick infusion of polyglucose and sodium chloride solution is beneficial to the recovery of erythrocyte rheological parameters before CPR
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".