Effect of atorvastatin on cognition and blood lipids in patients with different stages of vascular cognitive impairment
Bibliographic record
Abstract
Objective To study the effects of atorvastatin on cognition and blood lipids in patients with different stages of vascular cognitive impairment (VCI).Methods 140 patients with VCI were randomly divided into the treatment group [n = 75,VCI without dementia(VCIND) :47,vascular dementia (VaD):28] and the control group (n= 65 ,VCIND:41,VaD:24 ).The control group received conventional therapy,while the treatment group were administrated orally with 20 μg of atorvastatin every evening.The indices of TC,TG,HDL-C,LDL-C,as well as the scores of MMSE and clock-drawing test were compared between the groups before and 24 weeks after treatment.Results The plasma TC,TG,LDL-C decreased and the scores of MMSE and clock-drawing test improved significantly in the treatment group.The improvement in the scores of MMSE and clock-drawing test was greater in the VCIND treatment group than in the VaD treatment group.Conclusion Atorvastatin may improve cognitive function in patient with VCI,especially in VCIND patients.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".