Effect of atorvastatin on cognition and blood lipids in patients with different stages of vascular cognitive impairment
Why this work is in the frame
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Bibliographic record
Abstract
Objective To study the effects of atorvastatin on cognition and blood lipids in patients with different stages of vascular cognitive impairment (VCI).Methods 140 patients with VCI were randomly divided into the treatment group [n = 75,VCI without dementia(VCIND) :47,vascular dementia (VaD):28] and the control group (n= 65 ,VCIND:41,VaD:24 ).The control group received conventional therapy,while the treatment group were administrated orally with 20 μg of atorvastatin every evening.The indices of TC,TG,HDL-C,LDL-C,as well as the scores of MMSE and clock-drawing test were compared between the groups before and 24 weeks after treatment.Results The plasma TC,TG,LDL-C decreased and the scores of MMSE and clock-drawing test improved significantly in the treatment group.The improvement in the scores of MMSE and clock-drawing test was greater in the VCIND treatment group than in the VaD treatment group.Conclusion Atorvastatin may improve cognitive function in patient with VCI,especially in VCIND patients.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it