MétaCan
Menu
Back to cohort
Record W2395311482 · doi:10.5376/ijccr.2016.06.0017

Kallmann Syndrome with Panhypopituitarism and Uterine Agenesis

2016· article· en· W2395311482 on OpenAlexvenueno aff
M.A. Amani, N. Medjadi, B. Benlazaar

Bibliographic record

VenueInternational Journal of Clinical Case Reports · 2016
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSexual Differentiation and Disorders
Canadian institutionsnot available
Fundersnot available
KeywordsKallmann syndromeAgenesisMedicineGynecologyInternal medicineAnatomy

Abstract

fetched live from OpenAlex

We report the case of a female patient of 27 years with no particular family history and who consulted for primary amenorrhea. The clinical examination revealed a female morphotype with eunuchoid appearance. The patient was immature and had anosmia. Laboratory tests: FSH- 0.67mIU/L, LH-0.05mIU/L, Estradiol- 17pg/ml (gonadotropin deficiency), basic cortisol-264.72nmol /L, ACTH-6pg/ml (adrenocorticotropic deficiency), FT4-6.20 pmol/L, TSHus-3.11?IU/L (thyreotropic deficiency), PRL = 4.02ng/ml. The Karyotype was 46XX. The hypothalamic pituitary MRI revealed an agenesis of the olfactory bulbs (Fig.1). An abdominal ultrasound performed to search an associated renal malformation and completed with a pelvic MRI found a uterine agenesis (Fig.2), atrophic ovaries (right ovary-1cm³ and left ovary-2cm³, fig.3 and fig 4 respectively) and a malrotation of a small right kidney (fig.5). Our treatment consisted in a hormonal replacement therapy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.302
Threshold uncertainty score0.189

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.373
Teacher spread0.344 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

Explore more

Same venueInternational Journal of Clinical Case ReportsSame topicSexual Differentiation and DisordersFrench-language works237,207