← all works
Entecavir plus tenofovir combination therapy for chronic hepatitis B in patients with previous nucleos(t)ide treatment failure
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
The three-model screen
all 1,000 screened works →All three models called this out of scope.
stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high
Clinical study of entecavir plus tenofovir in chronic hepatitis B after treatment failure; a therapeutic efficacy question.
GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: high
This clinical study concerns combination therapy for chronic hepatitis B, not research practice.
Grok 4.5OUT
genre: empirical
about Canada: no
confidence: low
Clinical hepatology combination therapy for chronic hepatitis B; domain medicine, abstract missing.
Abstract
No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
The record
- Venue
- Hepatology International
- Topic
- Hepatitis B Virus Studies
- Field
- Medicine
- Canadian institutions
- University Health Network
- Funders
- Bristol-Myers Squibb
- Keywords
- EntecavirMedicineAdefovirTelbivudineLamivudineInternal medicineRegimenGastroenterologyClinical endpointHepatitis B virusEmtricitabineChronic hepatitisHepatitis BTenofovirVirologyVirusHuman immunodeficiency virus (HIV)Clinical trial
- Has abstract in OpenAlex
- no