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Record W2404604990 · doi:10.4140/tcp.n.2015.527

Polypharmacy, the Elderly, and Deprescribing

2015· article· en· W2404604990 on OpenAlexaff
Shirin Jetha

Bibliographic record

VenueThe Consultant Pharmacist · 2015
Typearticle
Languageen
FieldMedicine
TopicPharmaceutical Practices and Patient Outcomes
Canadian institutionsCanadian Pharmacists Association
Fundersnot available
KeywordsPolypharmacyDeprescribingMedicineBeers CriteriaOlder peopleHarmElderly peopleGeriatricsAcronymIntensive care medicineMedical emergencyPsychiatryGerontology

Abstract

fetched live from OpenAlex

The risks of polypharmacy are heightened in the elderly because of a number of factors including age-related physiologic changes and the presence of comorbid conditions. Polypharmacy is a strong predictor of potentially inappropriate medication (PIM) use in the elderly in which harm may outweigh potential benefits. Despite available lists and criteria of PIMs from expert panels regarding inappropriate use of medications for older adults, prescribing of PIMs continues to be reported. Empowering clinicians with evidence-based guidance to safely and effectively discontinue PIMs by "deprescribing" is the subject of current research. Pharmacists can play an important role as part of the circle of care for the elderly. The acronym "MINDFUL" serves as a reminder of steps commonly used by pharmacists to assess appropriateness of medications and optimize health outcomes for their senior patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.838
Threshold uncertainty score0.328

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.272
GPT teacher head0.420
Teacher spread0.148 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations40
Published2015
Admission routes1
Has abstractyes

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