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Record W2406174522 · doi:10.1017/s0317167100120876

An Evidence Based Approach to the First Unprovoked Seizure

2002· article· en· W2406174522 on OpenAlexaffvenue
Samuel Wiebe

Bibliographic record

VenueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · 2002
Typearticle
Languageen
FieldMedicine
TopicEpilepsy research and treatment
Canadian institutionsLondon Health Sciences CentreWestern University
Fundersnot available
KeywordsRelevance (law)Randomized controlled trialMEDLINEClinical significanceMedicineProcess (computing)Clinical trialPsychologyIntensive care medicineComputer scienceSurgeryPathology

Abstract

fetched live from OpenAlex

The objective is to illustrate the creation and structure of a particular type of Evidence Based Care (EBC) summary that has direct clinical relevance, the Critically Appraised Topic (CAT). The process consists of a step-by-step application of the EBC principles to a common neurological problem, i.e., a patient presenting with a first, unprovoked generalized seizure. This includes asking a focused clinical question about prognosis for recurrence and the role of antiepileptic drugs; searching the literature to answer the question; selecting the relevant evidence (a meta-analysis about prognosis and a randomized controlled trial about therapy); appraising the literature for its validity and usefulness; and applying the results to the clinical scenario. The result is a one-page, user friendly CAT whose title states a declarative answer to the clinical question. It also contains a description of the literature search and of the evidence, the clinical bottom lines derived from the evidence, and general comments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.053
metaresearch head score (Gemma)0.119
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.053
Threshold uncertainty score0.279

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0530.119
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0140.005
Science and technology studies0.0020.005
Scholarly communication0.0120.008
Open science0.0050.005
Research integrity0.0080.012
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.096
GPT teacher head0.308
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2002
Admission routes2
Has abstractyes

Explore more

Same venueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques→Same topicEpilepsy research and treatment→French-language works237,207→