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Record W2406613612 · doi:10.1093/ajhp/62.11.1122

Four countries shed light on drug-review policies

2005· article· en· W2406613612 on OpenAlexaboutno aff
Donna Young

Bibliographic record

VenueAmerican Journal of Health-System Pharmacy · 2005
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicHealth Systems, Economic Evaluations, Quality of Life
Canadian institutionsnot available
Fundersnot available
KeywordsCommonwealthAlliancePublic administrationPolitical scienceAdvisory committeePoliticsMedical prescriptionAltruism (biology)Prescription drugPublic relationsMedicineLawPsychologyPharmacology

Abstract

fetched live from OpenAlex

Drug policy is a mix of scientific evidence, judgment, altruism, self-interest, and politics that are superimposed on a complex, semirational, constantly changing, overburdened system, said Andreas Laupacis, chair of the Canadian Expert Drug Advisory Committee (CEDAC). Or at least, he said, that is what it feels like in Canada. But, Laupacis added, he takes comfort in knowing that other nations are also struggling with the same complex issues of how best to evaluate the effectiveness and safety of prescription drugs and determine which medications should be publicly funded. Laupacis joined representatives from the United Kingdom, Germany, the United States, and the pharmaceutical industry at an April 22 forum in Washington, D.C., to discuss methods used in conducting systematic reviews of prescription drugs, what other information is used in determining coverage, and the public’s and other stakeholders’ roles in the process. The Capitol Hill briefing was sponsored by two nonpartisan groups: the Commonwealth Fund and the Alliance for Health Reform.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.053
metaresearch head score (Gemma)0.104
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.053
Threshold uncertainty score0.282

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0530.104
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0060.008
Science and technology studies0.0080.012
Scholarly communication0.0350.014
Open science0.0030.014
Research integrity0.0250.021
Insufficient payload (model declined to judge)0.0140.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.225
GPT teacher head0.461
Teacher spread0.236 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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