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Record W2406815105 · doi:10.1055/s-0033-1337954

Editorial zum 80. Geburtstag von Prof. Riehm

2013· editorial· de· W2406815105 on OpenAlexaboutno aff
T. Klingebiel, Martin Schrappe

Bibliographic record

VenueKlinische Pädiatrie · 2013
Typeeditorial
Languagede
FieldHealth Professions
TopicChild and Adolescent Health
Canadian institutionsnot available
Fundersnot available
KeywordsPhilosophyMedicine

Abstract

fetched live from OpenAlex

Liebe Leserinnen und Leser, wir legen Ihnen einen Sonderband der Klinischen Pädiatrie vor, den wir Prof. Riehm zum 80. Geburtstag gewidmet haben. Der Beitrag von Prof. Riehm zur pädiatrischen Onkologie im Allgemeinen und zur Behandlung von Kindern mit Leukämien und malignen Lymphomen ist so fundamental, dass wir ihn zu seinem 80. Geburtstag in konzentrierter Form darstellen wollten. Es war uns wichtig, die Ideen und Gedanken lebendig werden zu lassen, mit denen Prof. Riehm vor mehr als 40 Jahren die Grundlagen für eine moderne pädiatrische Onkologie gelegt hat. Vor nicht allzu langer Zeit ist das Buch „Der König aller Krankheiten – Krebs eine Biografie“[ 1 ] von Siddhartha Mukherjee erschienen, das sehr plastisch und anschaulich die Entwicklung von Diagnostik und Therapie von Krebskrankheiten darstellt, jedoch den Beitrag von Prof. Riehm völlig ignoriert. Umso wichtiger erschienen es uns auch, wichtige Mitarbeiter und Mitstreiter im In- und Ausland, wie Prof. Helmut Gadner, Prof. Paul Gaynon, Prof. Karl Welte, Prof. Günter Henze, Prof. Alfred Reiter, Prof. Dietrich Niethammer und Prof. Fritz Lampert selbst zu Wort kommen zu lassen. Es erschien uns auch wichtig, in einer biographischen Darstellung Prof. Riehms Gedanken und Überlegungen authentisch zu ­dokumentieren. Der vorliegende Band zeigt die Entstehung und das, was aus den Gedanken geworden ist. Er eignet sich dazu, die Ideen nachzuvollziehen, ihre fundamentale Bedeutung zu verstehen, aber er eignet sich auch dazu, ihn als Dokumentation des State-of-the-Art von Diagnostik und Behandlung von akuten Leukämien und Lymphomen zu lesen. In einem Leukemia Sonderheft im Jahr 2010[ 2 ] heißt es treffend: “Because the treatment advances he developed were not always readily accepted by other groups working in the field, Dr Riehm spent a great deal of time and energy promoting the concept of ‘BFM’-type therapy around the world. To say that he was successful in this endeavor would be a major understatement. Today, BFM-type therapy is used in the United States, Canada, Europe, South America, Australia, New Zealand, the Middle East and Asia. Under the guidance and tutelage of Dr Riehm, an International BFM study group (I-BFM-SG) has been formed, with participation of a large number of countries, some with limited resources. An intercontinental consortium from the I-BFM-SG (called ALL-IC BFM) recently completed their first major clinical trial in a large group of countries from Latin America, East Europe and Asia, with results matching those attained by other major study groups. In fact, BFM type of therapy has also recently been adopted by various adult ALL study groups, resulting in significant improvement in cure rates. It is clear that Dr Riehm is one of the most influential oncologists in the modern era. He deserves special recognition for his pioneering and prodigious accomplishments, and we appreciate his ongoing friendship and support.” Wir gratulieren Prof. Riehm zu seinem Geburtstag und zu einer Lebensleistung, die das Leben tausender Kinder und Jugendlicher hat erhalten helfen. Wir danken allen Wissenschaftlern, Ärzten, Schwestern und technischen Mitarbeitern, die diesen großartigen Erfolg mit ermöglicht haben.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.006
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.031
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.006
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0030.000
Scholarly communication0.0000.001
Open science0.0020.001
Research integrity0.0070.013
Insufficient payload (model declined to judge)0.0050.036

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.353
Teacher spread0.331 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

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