Pergolide and cabergoline increased risk for valvular heart disease in Parkinson disease
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Bibliographic record
Abstract
EtiologyMay 1, 2007Pergolide and cabergoline increased risk for valvular heart disease in Parkinson diseaseDavid Massel, MD, Neville Suskin, MDDavid Massel, MDLondon Health Sciences Centre, London, Ontario, Canada (D.M., N.S.)Search for more papers by this author, Neville Suskin, MDLondon Health Sciences Centre, London, Ontario, Canada (D.M., N.S.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJC-2007-146-3-076 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookTwitterLinkedInRedditEmail Source CitationZanettini R, Antonini A, Gatto G, et al. Valvular heart disease and the use of dopamine agonists for Parkinson's disease. N Engl J Med. 2007;356:39-46. https://pubmed.ncbi.nlm.nih.gov/17202454Clinical Impact RatingsCardiology: Neurology: References1 Spatz M. Pathogenetic studies of experimentally induced heart lesions and their relation to carcinoid syndrome. Lab Invest. 1964;13:288-300. [PMID: 14127033] Google Scholar2 Connolly HM, Crary JL, McGoon MD, et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med. 1997;337:581-8. [PMID: 9271479] Google Scholar3 Roth BL. Drugs and valvular heart disease. N Engl J Med. 2007;356:6-9. [PMID: 17202450] Google Scholar4 Rothman RB, Baumann MH, Savage JE, et al. Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications. Circulation. 2000;102:2836-41. [PMID: 11104741] Google Scholar5 Clarke CE, Deane KH. Cabergoline for levodopa-induced complications in Parkinson's disease. Cochrane Database Syst Rev. 2001;(1):CD001518. [PMID: 11279720] Google Scholar Author, Article, and Disclosure InformationAffiliations: London Health Sciences Centre, London, Ontario, Canada (D.M., N.S.) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails May 1, 2007Volume 146, Issue 3Page: 76KeywordsAdverse eventsAortic valveBlood pressureBody mass indexCarcinoid tumorCardiovascular therapyCohort studiesCoronary heart diseaseDopamineDrugsHistamineHypertensionMedical risk factorsNeurologyOutpatient clinicsParkinson diseasePopulation statisticsSerotoninValvular diseases ePublished: 9 March 2020 Issue Published: May 1, 2007 Copyright & PermissionsCopyright © 2007 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it