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Record W2411243510 · doi:10.2310/6620.2008.08028

Thimerosal and the Relevance of Patch-Test Reactions in Children

2008· article· en· W2411243510 on OpenAlexvenueno aff
Andrew Breithaupt, Sharon E. Jacob

Bibliographic record

VenueDermatitis · 2008
Typearticle
Languageen
FieldMedicine
TopicContact Dermatitis and Allergies
Canadian institutionsnot available
Fundersnot available
KeywordsThimerosalMedicinePatch testThiomersalCosmeticsContact allergyDermatologySensitizationAllergic contact dermatitisContact dermatitisDisinfectantContact lensAllergyOphthalmologyImmunologyPathology

Abstract

fetched live from OpenAlex

Thimerosal (C(9)H(9)HgNaO(2)S) is a mercuric derivative of thiosalicylic acid that goes by many names. It has been used as a disinfectant (eg, Merthiolate) and as a preservative in some vaccines, cosmetics, tattoo inks, eye drops, and contact lens solutions. It remains one of the least likely chemicals to cause contact allergy and for this reason has been removed from many standard screening series. Positive patch-test reactions (demonstrating sensitization) may still be seen (especially in older children); however, these reactions are not clinically relevant and are expected to be fewer, reflecting changes in current vaccine formulations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.185

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.224
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations41
Published2008
Admission routes1
Has abstractyes

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