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Record W2412485776

Component analysis of verbal fluency in patients with schizophrenia.

2000· article· en· W2412485776 on OpenAlexaff
Konstantine K. Zakzanis, Angela K. Troyer, Jill B. Rich, Walter Heinrichs

Bibliographic record

VenuePubMed · 2000
Typearticle
Languageen
FieldMedicine
TopicSchizophrenia research and treatment
Canadian institutionsThe Scarborough HospitalUniversity of Toronto
Fundersnot available
KeywordsPsychologyVerbal fluency testSchizophrenia (object-oriented programming)FluencyAudiologyNeuropsychologyPsychosisNeuropsychological testCognitionRaw scoreAssociation (psychology)Frontal lobeCognitive psychologyDevelopmental psychologyNeurosciencePsychiatryMedicine
DOInot available

Abstract

fetched live from OpenAlex

OBJECTIVE: Clustering and-switching components of phonemic fluency performance were compared in patients with schizophrenia and healthy normal controls. BACKGROUND: These components were selected to provide evidence for a specific anatomic locus for the breakdown of language processes or for a multiple-disease model of schizophrenia. METHOD: As part of a larger battery of neuropsychological tests, phonemic fluency tests were administered on an individual basis. On separate 60-second trials, participants were instructed to generate words beginning with the letters C, F, and L, excluding proper names and variants of the same word. Three scores were obtained for each participant: (1) number of words generated, excluding errors and repetitions; (2) mean cluster size; and (3) raw number of switches. RESULTS: The patients showed small but significant impairments in clustering and larger impairments in switching relative to normal controls. CONCLUSIONS: This pattern suggests a relatively greater deficit in functioning in the frontal lobe than in the temporal lobe. However, neither measure was able to completely discriminate patients with schizophrenia from controls. Moreover, differences in fluency performance were observed among subtypes of schizophrenia. Taken together, the findings of impaired performance for both aspects of fluency, differences between subtypes, and the failure to completely discriminate patients with schizophrenia from controls indicate that there is not a single marker of the disease, at least among these fluency variables. Instead, the current findings are more supportive of a multiple-disease model of schizophrenia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.224
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations27
Published2000
Admission routes1
Has abstractyes

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