Influence of Some Psychoactive Drugs on Mineral Metabolism inMan
Bibliographic record
Abstract
A MAOI drug, phenelzine and two amino acids, tryptophan and glycine were administered serially to a group of patients with chronic schizophrenia for three-week periods. Measurements of body weight, of four electrolytes and two steroids were made at regular intervals. The research design included control of each variable and allowed for the presence in some patients only of tranquilizing drugs having anti-adrenalin and antiserotonin effects and of an anticholinergic drug. Analyses of variance were employed to evaluate the results. It was found that the following trends resulted. Introduction of phenelzine led to an increase in plasma sodium and a fall in magnesium. Tryptophan feeding brought about increases in plasma sodium, potassium, magnesium and calcium and a decrease in plasma corticoids and urinary 17-ketosteroids. The effect of phenothiazine and butyrophenone tranquilizing drugs was to increase plasma potassium and the plasma corticoids. Body weight changes were not relevant to these results.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".