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Record W2413579465

[Indications and outcomes of epilepsy surgery in children].

2006· article· en· W2413579465 on OpenAlexaff
E Sell-Marucco

Bibliographic record

VenuePubMed · 2006
Typearticle
Languageen
Field
Topic
Canadian institutionsSickKids FoundationHospital for Sick Children
Fundersnot available
KeywordsEpilepsy surgeryEpilepsyMedicineMagnetoencephalographyNeuroimagingPediatric epilepsyDrug Resistant EpilepsyPediatricsElectroencephalographyPsychiatry
DOInot available

Abstract

fetched live from OpenAlex

INTRODUCTION: One in every four children who suffer epilepsy will continue to seize despite all the current arsenal of anticonvulsant medications. Epilepsy surgery can be an effective treatment for many cases of pharmaco-resistant epilepsy. AIM: To review some of the most recent data regarding indication and results for epilepsy surgery in children. DEVELOPMENT: New analysis of neurophysiological data such as magnetoencephalography, dipole analysis and high frequency oscillations, plus functional neuroimaging and higher resolution MRI, have improved the prompt referral of potential candidates for surgery. An adequate selection of the surgical candidates will be fundamental in obtaining positive outcomes. Children, just like adults, can achieve seizure freedom or more than 90% seizure reduction in 85% of the cases of temporal lobe resections. Extratemporal epilepsy surgery is more challenging, and presents frequently in epilepsy surgery centres specialized in pediatric care. CONCLUSION: It is not mandatory for a patient to have an structural lesion evident on MRI in order to be considered a candidate for epilepsy surgery. In many cases a partial reduction of seizure activity can significantly improve the patient's and family's quality of life, and can have a sinergistic effect with other therapies which were no effective before surgery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.040

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0120.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.211
Teacher spread0.198 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2006
Admission routes1
Has abstractyes

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