Bibliographic record
Abstract
BACKGROUND: Because atopic dermatitis (AD) patients differ from non-AD patients in immunologic responses (they lack β-defensins, are more likely to react to protein allergens, and are harder to experimentally sensitize to the nonprotein allergens), patch-test responses to commercially available patch test series may differ in AD patients. OBJECTIVE: To compare responses to conventional patch tests in AD and non-AD patients and to assess the importance of specific allergens in AD. METHODS: AD patients were strictly defined by history of childhood flexural dermatitis. Patients with active disease were routinely pretreated with systemic antistaphylococcal and antiyeast antibiotics before patch testing unless contraindicated. All final patch-test readings occurred at day 7. RESULTS: The overall number of positive patch-test results did not differ significantly in AD patients (n = 146) versus non-AD patients (n = 1,003). There was no significant increase in nickel sensitivity. There was a nonsignificant trend toward an increased number of positive patch-test reactions to tixocortol pivalate, Compositae mix, and propylene glycol in AD patients. CONCLUSION: In AD patients treated with antibiotics and systemic azoles before patch testing, the number of positive patch-test reactions is almost identical to that of non-AD patients. Patch-test reactions to components of topical medicaments may be more frequent in AD as compared to non-AD patients.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".