Association of quetiapine with ischemic brain stem stroke: a case report and discussion
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Atypical antipsychotics (AAPs) are approved by the US Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder. Since the health regulatory agency of Canada (2002), the FDA (2003), and the European Medicines Agency (2004) reported an increased risk of cerebrovascular adverse events (CVAEs) from olanzapine and risperidone in clinical trials of elderly demented patients, there have been concerns about the risk of CVAEs associated with AAPs, and recent guidelines emphasize the importance of generating evidence for AAPs [Shin et al. 2013; Barnes, 2011]. In this article, an ischemic pontine stroke case probably related to quetiapine use is presented. Discussion of the case is of great importance because there are very limited data on the risk of CVAEs associated with the use of quetiapine,
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it