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Record W2416703676 · doi:10.1055/s-2007-1000047

Changing Pattern of Drug Utilization in a Neonatal Intensive Care Unit

2008· article· en· W2416703676 on OpenAlexaff
Jacob V. Aranda, Susanna Clarkson, Judith M. Collinge

Bibliographic record

VenueAmerican Journal of Perinatology · 2008
Typearticle
Languageen
FieldMedicine
TopicNeonatal Respiratory Health Research
Canadian institutionsMontreal Children's Hospital
Fundersnot available
KeywordsMedicineDrugNeonatal intensive care unitAmpicillinGentamicinPenicillinKanamycinChloramphenicolAntibioticsPediatricsIntensive care medicinePharmacologyMicrobiology

Abstract

fetched live from OpenAlex

Drug exposures in neonates admitted to a neonatal intensive care unit in 1974 and in 1977 were compared. A significant increase in drug exposure (3.4 drugs per baby in 1974 versus 6.19 drugs in 1977) and in the total number of drugs used (71 versus 102 different drugs) were noted. The proportion of infants receiving no drugs were similar (23%). Infants given penicillin and kanamycin decreased by about 50% with a reciprocal increase observed with ampicillin and gentamicin. Except for a few drugs (chloramphenicol, methicillin, Infantol), all drugs were used in a greater number of babies in 1977. Data indicate increase in drugs used and a change in the pattern of drug utilization over a period of three years.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.781
Threshold uncertainty score0.356

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.385
Teacher spread0.323 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2008
Admission routes1
Has abstractyes

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