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Record W2416946533 · doi:10.1016/j.jaci.2016.03.025

MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

2016· review· en· W2416946533 on OpenAlexaff
Jean Bousquet, Holger J. Schünemann, Peter W. Hellings, S. Arnavielhe, Claus Bachert, Anna Bedbrook, Karl‐Christian Bergmann, Sinthia Bosnic‐Anticevich, Jan Brożek, Moisés A. Calderón, Giorgio Walter Canonica, Thomas B. Casale, Niels H. Chavannes, Linda Cox, Henry Chrystyn, Álvaro A. Cruz, Ronald Dahl, Giuseppe De Carlo, Pascal Demoly, P. Devillier, Gérard Dray, Monica Fletcher, Wytske J. Fokkens, João Fonseca, Sandra Nora González Díaz, Lawrence D. Grouse, Thomas Keil, Piotr Kuna, Désirée Larenas‐Linnemann, Karin C. Lødrup Carlsen, Eli O. Meltzer, Jaoquim Mullol, Antonella Muraro, Robert N. Naclerio, Susanna Palkonen, Nikolaos G. Papadopoulos, Giovanni Passalacqua, David Price, Dermot Ryan, Bolesław Samoliński, Glenis K. Scadding, Aziz Sheikh, François Spertini, Arunas Valiulis, Erkka Valovirta, Samantha Walker, Magnus Wickman, Arzu Yorgancıoğlu, Tari Haahtela, Torsten Zuberbier, Werner Aberer, Mitsuru Adachi, Ioana Agache, Cezmi A. Akdiş, Mübeccel Akdis, Isabella Annesi-Maesano, Ignacio J. Ansotegui, Josep M Antó, Syed Hasan Arshad, Ilaria Baiardini, Аbay Baigenzhin, Cristina Bárbara, Eric D. Bateman, Bianca Beghé, Elisabeth H. Bel, Kazi Saifuddin Bennoor, Michael K. D. Benson, David N. Bernstein, Bewick Michael, Bieber Thomas, Carsten Bindslev‐Jensen, Leif Bjermer, Hubert Blain, Attilio Boner, Matteo Bonini, С. Бонини, Isabelle Bossé, Jacques Bouchard, Louis‐Philippe Boulet, Rodolphe A. Bourret, Philippe‐Jean Bousquet, Fulvio Braido, Andrew Briggs, Christopher E. Brightling, Roland Buhl, Peter Burney, Andrew Bush, F. Caballero-Fonseca, Davide Caimmi, Paulo Augusto Moreira Camargos, T. Camuzat, Kai‐Håkon Carlsen, Warner Carr, Alfonso Cepeda Sarabia, Leda Chatzi, Yuzhi Chen, R. Chiron, Ekaterine Chkhartishvili, А. Г. Чучалин, Ieva Cirule, Jaime Correia de Sousa, David Costa, George Crooks, Adnan Čustović, Ulf Darsow, F. de Blay, Esteban De Manuel Keenoy, Tony Dedeu, Diana Deleanu, Judah A. Denburg, A. Didier, Anh Tuan Dinh‐Xuan, Dejan Dokic, H. Douagui, Rūta Dubakienė, Stephen R. Durham, Mark S. Dykewicz, Yehia El‐Gamal, Regina Emuzyte, Antje Fink-Wagner, Alessandro Fiocchi, Francesco Forastiere, Amiran Gamkrelidze, Bilun Gemicioğlu, José E. Gereda, Roy Gerth van Wijk, Maia Gotua, Ineta Grisle, M. Antonieta Guzmán, Joachim Heinrich, B. Hellquist-Dahl, Friedrich Horak, Peter Howarth, Marc Humbert, Michael E. Hyland, Juan Carlos Ivancevich, Edgardo Járes, Sebastian L. Johnston, O. Jonquet, Guy Joos, Ki‐suck Jung, J. Just, Marek Jutel, Ігор Петрович Кайдашев, Musa Khaitov, Ömer Kalayci, Paul K. Keith, Nikolaï Khaltaev, Jörg Kleine‐Tebbe, Ludger Klimek, B. Koffi N’Goran, Gerard H. Koppelman, Marek L. Kowalski, Inger Kull, Violeta Kvedarienė, Bart N. Lambrecht, Susanne Lau, Daniel Laune, Lan Le Thi Tuyet, Jing Li, Phillipe Lieberman, Brian J. Lipworth, Renaud Louis, Y. Magard, A. Magnan, Bassam Mahboub, I. Majer, Mika J. Mäkelä, Peter J. Manning, Marcus Maurer, Sandra Mavale-Manuel, Erik Melén, E. Melo-Gomes, Jacques Mercier, Hans Merk, Neven Miculinić, Florin Mihălţan, Branislava Milenković, Yousser Mohammad, Mathiéu Molimard, Isabelle Momas, A. Montilla-Santana, Mário Morais‐Almeida, Ralph Mösges, Rachel Nadif, Leyla S. Namazova-Baranova, Hugo Neffen, K Nékám, Angelos Neou, B. Niggemann, Dieudonné T. Nyembue, Robyn E. O’Hehir, Ken Ohta, Yoshitaka Okamoto, K. Okubo, S. Ouedraogo, Pier-Luigi Paggiaro, Isabella Pali‐Schöll, Stephen Palmer, Petr Panzner, Alberto Papi, Hae‐Sim Park, Ian Pavord, Ruby Pawankar, Oliver Pfaar, Robert Picard, Bernard Pigearias, Isabelle Pin, Davor Plavec, Wolfgang Pohl, Todor A. Popov, Dirkje S. Postma, Paul Potter, Lars K. Poulsen, Klaus F. Rabe, Filip Raciborski, Françoise Radier Pontal, Sakari Reitamo, Maria-Susana Repka-Ramirez, Carlos Robalo Cordeiro, Graham Roberts, Francisco Ródenas, Christine Rolland, Miguel Román-Rodríguez, Antonino Romano, José Rosado‐Pinto, Nelson Augusto Rosário Filho, Larry Rosenwasser, Menachem Rottem, Mario Sánchez‐Borges, Joaquim Sastre-Dominguez, Peter Schmid‐Grendelmeier, E Sancho Serrano, F. Estelle R. Simons, Juan‐Carlos Sisul, Ingebjørg Skrindo, Henriëtte A. Smit, Dírceu Solé, Talant Sooronbaev, Otto Spranger, Rafaël Stelmach, Timo Strandberg, Jordi Sunyer, Carel Thijs, Ana Todo‐Bom, Massimo Triggiani, Rudolf Valenta, Antonio Valero, Marianne van Hage, Olivier Vandenplas, G. Vezzani, Pakit Vichyanond, Giovanni Viegi, Martin Wagenmann, Ulrich Wahn, D. Gwyn Williams, John Wright, Barbara P. Yawn, Panayiotis K. Yiallouros, Osman Yusuf, Heather J. Zar, Mario Zernotti, Luo Zhang, Nanshan Zhong, Mihaela Zidarn

Bibliographic record

VenueJournal of Allergy and Clinical Immunology · 2016
Typereview
Languageen
FieldMedicine
TopicAllergic Rhinitis and Sensitization
Canadian institutionsMcMaster University
FundersAllergopharmaGlenmark PharmaceuticalsEli Lilly and CompanyAstraZenecaRespiratory Effectiveness GroupUniversity of ChicagoRegeneron PharmaceuticalsTeva Pharmaceutical IndustriesEuropean CommissionSanofiAmgenBritish Lung FoundationPfizerMylanGlaxoSmithKline
KeywordsClinical decision makingMedicineComputer scienceAlgorithmIntensive care medicine

Abstract

fetched live from OpenAlex

The selection of pharmacotherapy for patients with allergic rhinitis (AR) depends on several factors, including age, prominent symptoms, symptom severity, control of AR, patient preferences, and cost. Allergen exposure and the resulting symptoms vary, and treatment adjustment is required. Clinical decision support systems (CDSSs) might be beneficial for the assessment of disease control. CDSSs should be based on the best evidence and algorithms to aid patients and health care professionals to jointly determine treatment and its step-up or step-down strategy depending on AR control. Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR [fighting chronic diseases for active and healthy ageing]), one of the reference sites of the European Innovation Partnership on Active and Healthy Ageing, has initiated an allergy sentinel network (the MACVIA-ARIA Sentinel Network). A CDSS is currently being developed to optimize AR control. An algorithm developed by consensus is presented in this article. This algorithm should be confirmed by appropriate trials.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.009
Threshold uncertainty score0.032

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.015
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0020.001
Open science0.0020.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0090.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.364
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations172
Published2016
Admission routes1
Has abstractyes

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Same venueJournal of Allergy and Clinical ImmunologySame topicAllergic Rhinitis and SensitizationFrench-language works237,207