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Record W2418184386

Workshop report: identification of research needs breast cancer etiology.

2001· article· en· W2418184386 on OpenAlexaffabout
Christine M. Friedenreich, Loraine D. Marrett

Bibliographic record

VenuePubMed · 2001
Typearticle
Languageen
FieldMedicine
TopicCancer Risks and Factors
Canadian institutionsAlberta Cancer Foundation
Fundersnot available
KeywordsMedicineBreast cancerEtiologyPsychosocialDiseaseFamily medicineCancerEnvironmental healthGerontologyPathologyInternal medicinePsychiatry
DOInot available

Abstract

fetched live from OpenAlex

A workshop to evaluate the scientific evidence for the etiologic associations between modifiable lifestyle and environmental risk factors and to identify areas for future research in breast cancer etiology was sponsored jointly by the Canadian Breast Cancer Initiative and the Canadian Breast Cancer Research Initiative in May, 2001. Reviews of the scientific evidence in these topics were commissioned and an expert panel convened to consider the reviews and make recommendations for research. The panel concluded that there was substantial evidence to proceed with additional research in several areas of breast cancer etiology. Particular support for future research for several lifestyle and environmental risk factors including alcohol, diet, physical activity, anthropometric factors, hormonally active agents and occupational exposures was identified. Several emerging hypotheses for breast cancer etiology were also considered and recommendations made in these areas. Specific areas for future consideration included: insulin-like growth factors, pharmaceuticals, viruses, psychosocial factors, and functional polymorphisms. The panel also identified common themes for future research including: studies of exposures across the life cycle; research in populations with unusual exposure levels; consideration of effect modification; development of improved exposure assessment methods and use of intermediate endpoints; separation of disease subtypes by hormone receptor status, stage and tumour markers; and consideration of biological mechanisms in breast cancer etiology.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.309
Threshold uncertainty score0.202

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.099
GPT teacher head0.390
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2001
Admission routes2
Has abstractyes

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