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Record W2418301606 · doi:10.1387/ijdb.11206331

Cell morphology in amphioxus nerve cord may reflect the time course of cell differentiation

2000· article· en· W2418301606 on OpenAlexafffund
Thurston C. Lacalli

Bibliographic record

VenueThe International Journal of Developmental Biology · 2000
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicDevelopmental Biology and Gene Regulation
Canadian institutionsUniversity of Saskatchewan
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsBiologyNeuroepithelial cellNeurulationVentral nerve cordAnatomySpinal cordApex (geometry)Cell biologyDorsumNeural plateEmbryoCellNeuroscienceEmbryogenesisNervous systemNeural stem cellStem cellGastrulation

Abstract

fetched live from OpenAlex

Amphioxus embryos elongate following neurulation, and this lengthens the developing nerve cord. Most neurons and support cells remain attached at their apices to the neuroepithelium, and the apices themselves become correspondingly longer. In consequence, apex length can be used in some instances as a measure of whether a given cell last divided before elongation or after, and approximately when. The data indicate that most floorplate, ependymoglial and infundibular cells are generated comparatively early, before most neurons. Among the neurons, the segmentally arranged DC (dorsal compartment) motoneurons appear to be among the first to develop, which accords with molecular data on the time course of neural development, using neurogenin and islet as markers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.071
Threshold uncertainty score0.358

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.256
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2000
Admission routes2
Has abstractyes

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