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Record W2418807116

[Prophylaxis and therapy of hepatitis B after liver transplantation].

2005· article· en· W2418807116 on OpenAlexaboutno aff
Nikola Bradarić

Bibliographic record

VenuePubMed · 2005
Typearticle
Languageen
FieldMedicine
TopicHepatitis B Virus Studies
Canadian institutionsnot available
Fundersnot available
KeywordsHBeAgMedicineVirologyHepatitis B virusHBsAg
DOInot available

Abstract

fetched live from OpenAlex

About 25% of all liver transplantations in USA are performed for liver disease due to viral hepatitis, 25% of them related to hepatitis B. It is also known that 90%-100% of transplanted persons with proven replicative stage of hepatitis B [HBeAg (+), HBV DNA (+)] develop reinfection of the transplanted liver in the absence of prophylaxis. This percentage is lower (30%-50%) in patients with nonreplicative stage of infection [HBeAg (-), HBV DNA (-)]. The consequence of most transplant infections is death due to the transplanted organ failure. The prophylaxis of infection is possible, however a combination of intravenous hepatitis B hyperimmune gammaglobulin and lamivudin may be too expensive for some transplantation centers in less developed countries. The aim of this article is to recommend prophylaxis and treatment of recurrent hepatitis B in persons with transplanted liver using data of the Consensus Conference on Hepatitis B in Geneva 2002, Canadian Consensus Group for Hepatitis (CASL) and EASL International Consensus Conference on Hepatitis B that should be available for patients in Croatia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.225
Teacher spread0.207 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2005
Admission routes1
Has abstractyes

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