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Record W2421038472 · doi:10.1016/s0924-9338(15)31852-6

Population Growth Rates of Psychosis and Effective Interventions

2015· article· en· W2421038472 on OpenAlexaffabout
Romella Durrani, Avril Deegan, David Cawthorpe

Bibliographic record

VenueEuropean Psychiatry · 2015
Typearticle
Languageen
FieldMedicine
TopicSchizophrenia research and treatment
Canadian institutionsChild, Adolescent and Family Mental HealthUniversity of Calgary
Fundersnot available
KeywordsRisperidoneOlanzapinePsychosisQuetiapinePsychiatryMedicinePopulationPsychological interventionSchizophrenia (object-oriented programming)Meta-analysisQuetiapine FumaratePsychologyAntipsychoticAtypical antipsychoticInternal medicineEnvironmental health

Abstract

fetched live from OpenAlex

Limited research is available on children and adolescent psychosis. Thus, we conducted a Meta-Analysis of pharmaceutical treatments, using literature from the last 5 years. A 16 year cumulative prevalence of psychosis in the Calgary Health Region was also examined. Conduct a Meta-Analysis to determine effective treatments for children and adolescent psychosis. Conduct a prevalence study for the Calgary Health Zone from 1994-2009. Update and identify effective treatment interventions for children and adolescent psychosis, and determine psychosis prevalence in the Calgary Health Region. Direct physician billing data was used for the Calgary Health Region (Alberta) from 1994-2009 (n = 763449) to identify 73078 unique individuals (30762-males, 42316-females), each of whom had a physician-assigned diagnosis of psychosis. Using standard methods, 41 studies were identified and those meeting inclusion criteria were compared and ranked on the basis of effect size, study design, etc. across studies. The 16 year cumulative prevalence of psychosis per 10,000 was 1026 for all ages, and 229 under 19. 4 studies met measurable outcomes; 34 results were positive, 17 were equivalent, and no results were negative. The greatest effect size was 1.03, while the lowest was −0.286. Risperidone, Quetiapine, and Olanzapine were effective treatments. Risperidone, Quetiapine, and Olanzapine are effective treatments for children and adolescent psychosis. Psychosis rates increased 2.3 times for all ages, and 2 times under age 19, from 1994-2009. Psychosis in the under 19 male population is becoming more prevalent and increasing at a higher rate compared to females.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.056
metaresearch head score (Gemma)0.115
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.056
Threshold uncertainty score0.296

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0560.115
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0080.032
Bibliometrics0.0100.011
Science and technology studies0.0010.002
Scholarly communication0.0040.005
Open science0.0020.003
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0080.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.353
Teacher spread0.314 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes2
Has abstractyes

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