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Record W2422424940 · doi:10.5530/pj.2016.3.5

Updates on Traditional Medicinal Plants for Hepatocellular Carcinoma

2016· article· en· W2422424940 on OpenAlexaff
Shilu Mathew, Muhammad Faheem, Mohd Suhail, Kaneez Fatima, Govindaraju Archunan, Nargis Begum, Muhammad Ilyas, Esam I. Azhar, Ghazi A. Damanhouri, Ishtiaq Qadri

Bibliographic record

VenuePharmacognosy Journal · 2016
Typearticle
Languageen
FieldHealth Professions
TopicDiverse Scientific Research Studies
Canadian institutionsInstitute of Infection and Immunity
Fundersnot available
KeywordsTerminalia chebulaTraditional medicineMedicineAndrographis paniculataHepatocellular carcinomaPharmacologyCancer researchAlternative medicinePathology

Abstract

fetched live from OpenAlex

Aim: Hepatocellular carcinoma (HCC) is a major worldwide problem primarily caused by hepa titis B and C virus infection. End stage liver cancer treatment options are limited thus requiring expensive liver transplantation which is not available in many countries. Methods: Several herbal compounds and herbal composite formulas have been studied through in-vitro and in vivo as an anti-HCC agent, enhancing our knowledge about their biological functions and targets. In this article, arecent update on the herbal medicine has been provided with reference to liver cancer. Results: For the sake of clarity, the effective herbal compounds, clinical studies of herbal composite formula, cell culture, and animal model studies safety are discussed. The effects of many herbal active compounds of Annona atemoya, Andrographis paniculata, Boerha viadiffusa, Piper longum, Podophyllum hexandrum, Phyllanthus amarus, and Terminalia chebula, and herbal composite formula on autophagy, apoptosis, antioxidant, and inflammation characteristicshave been provided. Conclusion: This will enhance our un-derstanding on the prevention and treatment of HCC by herbal active compounds and herbal composite formulas.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.017
Threshold uncertainty score0.058

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0170.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.311
GPT teacher head0.472
Teacher spread0.160 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2016
Admission routes1
Has abstractyes

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