Isolation and Characterization of Porins from H. pylori
Bibliographic record
Abstract
The outer membranes of Gram-negative bacteria represent selective, permeability barriers to environmental molecules. This function is accomplished in two ways. First, outer membranes exclude many larger hydrophilic molecules, including enzymes and other proteins, and most hydrophobic ones, by virtue of their unique composition. It has been demonstrated in Escherichia coli that outer membranes are asymmetric bilayers containing a unique species of glycolipid, lipopolysaccharide (LPS), in its outer leaflet, and phospholipids in its inner leaflet. The highly negatively charged LPS is stabilized by divalent cations. The observations that Helicobacter outer membrane proteins are Triton X-100 insoluble in the absence of EDTA or NaCl (1,2), that Helicobacter contains substantial amounts of LPS 3, and that Helicobacter is resistant to highly hydrophobic antibiotics, such as trimethoprin and nalidixic acid (4), lead one to believe that this organism is thematically similar.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".