Erythema Annulare Centrifugum in a Patient with Crohn Disease
Bibliographic record
Abstract
Background: Erythema annulare centrifugum (EAC) represents a hypersensitivity reaction to a variety of conditions, many of which have been reported in the literature. Methods and Results: We report on a 38-year-old woman with a 5-year history of recurrent polycylic, arcuate, scaly, erythematous patches with central clearing on her thighs and trunk. Clinical examination and biopsy were both consistent with a diagnosis of EAC. Two years after the initial presentation, she was diagnosed with mild Crohn disease. Conclusions: The prolonged nature of EAC in our patient and our inability to identify known associations of malignancies, including medications, connective tissue disorders, systemic disorders, and infections, led us to postulate that her EAC was related to her Crohn disease. A thorough review of the literature failed to detect any previous reports linking Crohn disease and EAC. Renseignements de base: L'érythème centrifuge (EAC) représente une réaction d'hypersensibilité à une variété de conditions dont beaucoup ont été signalées dans la littérature. Méthodes et résultats: Nous présentons un rapport sur le cas d'une femme de 38 ans présentant 5 ans d'antécédents de taches érythémateuses squameuses, arquées, polycycliques récurrentes avec guérison centrale sur les cuisses et le tronc. L'examen clinique et la biopsie étaient tous les deux compatibles avec un diagnostic d'EAC. Deux ans après la présentation initiale, elle a été diagnostiquée avec une forme bénigne de la maladie de Crohn. Conclusions: La nature prolongée de l'EAC chez notre patiente, et notre incapacité à identifier les associations connues, y compris les médicaments, les maladies du tissu conjonctif, les troubles systémiques, et des infections, des tumeurs malignes, nous a conduit à postuler que son EAC était lié à sa maladie de Crohn. Un examen approfondi de la littérature ne nous a pas permis de trouver des rapports antérieurs qui établissent un lien entre la maladie de Crohn et l'EAC.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".