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Record W2440631946 · doi:10.1097/olq.0000000000000403

A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men

2016· review· en· W2440631946 on OpenAlexaffabout
Jennifer Gratrix, Judith Brandley, Marla Dane, Sabrina S. Plitt, Petra Smyczek, Ron Read, Ameeta E. Singh

Bibliographic record

VenueSexually Transmitted Diseases · 2016
Typereview
Languageen
FieldImmunology and Microbiology
TopicReproductive tract infections research
Canadian institutionsUniversity of AlbertaPublic Health Agency of CanadaAlberta Health Services
Fundersnot available
KeywordsMedicineAzithromycinDoxycyclineChlamydiaMen who have sex with menRetrospective cohort studyChlamydia trachomatisInternal medicineGynecologyAntibioticsVirologyImmunologySyphilisHuman immunodeficiency virus (HIV)Microbiology

Abstract

fetched live from OpenAlex

In Brief We examined the prevalence of rectal chlamydia treatment failures in men who have sex with men and women attending Alberta sexually transmitted infection clinics. Among those completing a test of cure, there was no significant difference among patients treated initially with azithromycin (treatment failure, 39/460 [8.5%]; 95% confidence interval, 5.9%–11.0%) compared with patients treated with doxycycline (0/16; 95% confidence interval, 0%–0.2%; P = 0.63). No treatment failures for rectal chlamydia were found using doxycycline (0/16; 95% CI, 0%–0.2%) when compared with azithromycin (39/460 [8.5%]; 95% CI, 5.9%–11.0%; P = 0.63).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.928
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.330
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations14
Published2016
Admission routes2
Has abstractyes

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