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Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

2016· article· en· 1,488 citations· W2460752692 on OpenAlex· 10.1016/j.cmet.2016.06.004

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Cell Metabolism
Topic
Immune cells in cancer
Field
Immunology and Microbiology
Canadian institutions
McGill UniversityMcGill University Health Centre
Funders
National Center for Research ResourcesNational Institute of Diabetes and Digestive and Kidney DiseasesNational Institute of Arthritis and Musculoskeletal and Skin DiseasesNational Institute of Allergy and Infectious DiseasesNational Human Genome Research InstituteNational Institutes of HealthRegeneron PharmaceuticalsDeutsches KrebsforschungszentrumDeutsche ForschungsgemeinschaftCanadian Institutes of Health ResearchU.S. Department of Veterans AffairsNational Heart, Lung, and Blood InstituteUniversity of California, DavisMcGill University
Keywords
EffectorMacrophageInflammationCitric acid cycleMitochondrionCell biologyBiologyCytokineRegulatorMetabolic pathwayBiochemistryMetabolismIn vivoSuccinate dehydrogenaseIn vitroImmunology
Has abstract in OpenAlex
no