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Record W2461051094 · doi:10.1111/micc.12292

Comprehensive <i>In Situ</i> Analysis of Arteriolar Network Geometry and Topology in Rat Gluteus Maximus Muscle

2016· article· en· W2461051094 on OpenAlexafffund
Mohammed Al Tarhuni, Daniel Goldman, Dwayne N. Jackson

Bibliographic record

VenueMicrocirculation · 2016
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Health and Disease Prevention
Canadian institutionsWestern University
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsTopology (electrical circuits)GeometryAnatomyFunction (biology)Skeletal muscleFractalMathematicsComputer scienceBiologyMathematical analysisCombinatoricsCell biology

Abstract

fetched live from OpenAlex

OBJECTIVES: To provide detailed geometric and topological descriptions of the rat gluteus maximus arteriolar network, and to measure the distribution of diameters and lengths as well as their associated variability within and between networks. METHODS: Complete arteriolar networks arising from feed artery (inferior gluteal artery) to terminal branches were imaged under baseline conditions, using IVVM. Photomontages of complete networks were assembled and evaluated offline for measurements of geometry and topology. Single-line (skeletonized) tracings of the networks were made for fractal analysis. RESULTS: Diameters and lengths decreased with increasing topological order (centrifugal), while number of elements increased with increasing order. Horton's laws were shown to be valid within the arteriolar networks of the rat GM. Inter-network variability in diameter (~5-22%) and length (~17-30%) at each order was generally lower than the corresponding intra-network variability in diameter (~10-48%) and length (~39-106%). CONCLUSIONS: Data presented in this study provide crucial quantitative analysis of complete arteriolar networks within healthy skeletal muscle, and may serve as ideal experimental inputs for future theoretical studies of skeletal muscle microvascular structure and function.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.263
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2016
Admission routes2
Has abstractyes

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