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Record W2462002821 · doi:10.1385/1-59259-242-2:015

Linking Image Quantitation and Data Analysis

2003· review· en· W2462002821 on OpenAlexaff
Gregory Bloom, Peter W. Gieser, Emmanuel Lazaridis

Bibliographic record

VenueHumana Press eBooks · 2003
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Bioinformatics, and Biomedical Research
Canadian institutionsImpact
Fundersnot available
KeywordsDensitometryQualitative analysisImage (mathematics)Quantitative analysis (chemistry)SpotsSimple (philosophy)Computer scienceArtificial intelligencePattern recognition (psychology)ChemistryChromatographyPhysicsOpticsQualitative research

Abstract

fetched live from OpenAlex

Until recently, image-based experimentation in molecular biology has been primarily concerned with qualitative results produced as a result of such experiments as Northern blots, immunoblotting, and gel electrophoresis. These experiments result in a relatively small number of bands on an autorad or other imaging medium. These bands or spots would be visually inspected to determine their “presence” or “absence,” or visually compared with other spots on the medium to determine their relative intensities. Sometimes, comparisons would be enhanced using quantities derived from densitometry analysis. Such comparisons were often performed to provide a numerical summary of a clearly visible difference. This summary may have been required for publication of the experimental results. This approach seemed to serve the investigator well because there existed no real need for accurate image quantitation or data analysis and a simple qualitative result would suffice. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.037
Threshold uncertainty score0.123

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0160.017
Meta-epidemiology (narrow)0.0040.002
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0180.013
Science and technology studies0.0020.003
Scholarly communication0.0050.004
Open science0.0070.005
Research integrity0.0020.006
Insufficient payload (model declined to judge)0.0370.044

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.184
GPT teacher head0.419
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2003
Admission routes1
Has abstractyes

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