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Generation of Lactococcus lactis capable of coexpressing epidermal growth factor and trefoil factor to enhance in vitro wound healing

2015· article· en· 20 citations· W2463906378 on OpenAlex· 10.1007/s00253-015-6542-0

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

The three-model screen

all 1,000 screened works →

All three models called this out of scope.

stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

Microbiology engineering of Lactococcus lactis for wound healing; abstract absent but the title is unambiguous.

GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: high

It reports a microbiology and wound-healing experiment, not research practice.

Grok 4.5OUT
genre: empirical
about Canada: no
confidence: high

Title indicates applied microbiology wound-healing work; empty abstract but domain object is unambiguous.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Applied Microbiology and Biotechnology
Topic
Antimicrobial Peptides and Activities
Field
Immunology and Microbiology
Canadian institutions
University of Guelph
Funders
Keywords
Lactococcus lactisWound healingEpidermal growth factorRecombinant DNABiologyWestern blotMicrobiologyGrowth factorBiochemistryImmunologyBacteriaLactic acid
Has abstract in OpenAlex
no