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Record W2465761866

Subclinical hypothyroidism: When to treat, when to watch?

2004· article· en· W2465761866 on OpenAlexaff
Vahab Fatourechi

Bibliographic record

Venue˜The œconsultant · 2004
Typearticle
Languageen
FieldMedicine
TopicThyroid Disorders and Treatments
Canadian institutionsInstitute of Nutrition, Metabolism and Diabetes
Fundersnot available
KeywordsMedicineSubclinical infectionPregnancyAnticipation (artificial intelligence)PediatricsGoiterInternal medicineAdverse effectThyroidEndocrinologyGastroenterology
DOInot available

Abstract

fetched live from OpenAlex

Before a diagnosis of subclinical hypothyroidism is made, other causes of elevated thyroid-stimulating hormone (TSH), such as recovery from a serious acute illness, must be ruled out. Diagnosis is based on at least 2 assays performed over a period of several weeks. If the screening TSH levels are abnormal, measurement of serum free thyroxine is needed to confirm the diagnosis. Although patients who have TSH levels in the upper limit of the traditional normal range may be at higher risk for progression to hypothyroidism, no evidence exists for adverse health consequences. For patients with serum TSH levels in the range of 5.1 to 10 mlU/l., consider such factors as age, comorbidities, symptoms of hypothyroidism, pregnancy or anticipation of pregnancy, and the presence of goiter or antithyroid antibodies in the decision to treat. Thyroxine therapy is recommended for patients with serum TSH levels above 10 mlU/L.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.015
Threshold uncertainty score0.051

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0020.004
Open science0.0010.001
Research integrity0.0060.005
Insufficient payload (model declined to judge)0.0150.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.286
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2004
Admission routes1
Has abstractyes

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