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Record W2467347315

Anesthesia for Nelson's syndrome.

2009· article· en· W2467347315 on OpenAlexaboutno aff
Madhur Mehta, Girija P. Rath, Gyaninder Pal Singh

Bibliographic record

VenuePubMed · 2009
Typearticle
Languageen
FieldMedicine
TopicPituitary Gland Disorders and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicinePrednisoloneEuthyroidLabrador RetrieverEndocrine systemAnesthesiaEndocrinologyInternal medicineSurgeryHormone
DOInot available

Abstract

fetched live from OpenAlex

A 12 yr-old, 30 kg female child was admitted with history of bilateral adrenalectomy for Cushing’s syndrome 3 years back, following which she developed severe darkening of skin all over body and gradually progressing headache. Her endocrine profile revealed ACTH levels of 220 pg/mL (Normal = 6-76 pg/mL) with cortisol of 1.2 μg/dL (normal = 5-25 μg/dL) for which prednisolone 5 mg and fludrocortisone 50 μg daily were being supplemented. Growth hormone levels were increased (4 ng/mL; normal <2 ng/mL). Well defined hypointense mass (9 × 3 mm) arising from anterior pituitary was evident in CT scan. A diagnosis of Nelson’s syndrome was made and sublabial transsphenoidal hypophysectomy was planned. Child was rendered euthyroid on eltroxin 50 μg daily. Airway examination revealed coarse facies with Mallampati II airway.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.236
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

Explore more

Same venuePubMed→Same topicPituitary Gland Disorders and Treatments→French-language works237,207→