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Record W2472217800 · doi:10.1007/978-1-4939-1053-3_5

Generation of Effective Libraries by Neutral Drift

2014· article· en· W2472217800 on OpenAlexafffund
Miriam Kaltenbach, Nobuhiko Tokuriki

Bibliographic record

VenueMethods in molecular biology · 2014
Typearticle
Languageen
FieldMedicine
TopicPancreatic function and diabetes
Canadian institutionsCanada's Michael Smith Genome Sciences CentreUniversity of British Columbia
FundersCanadian Institutes of Health Research
KeywordsNeutral theory of molecular evolutionNeutral mutationNeutral networkPositive selectionFunction (biology)Sequence spaceMutagenesisSelection (genetic algorithm)Directed evolutionDirected Molecular EvolutionGenetic driftDiversity (politics)Sequence (biology)MutationBiologyComputer scienceGeneticsMathematicsArtificial intelligenceGeneGenetic variationPolitical science

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.005
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.007
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0020.003
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0050.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.367
Teacher spread0.343 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations14
Published2014
Admission routes2
Has abstractno

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Same venueMethods in molecular biology→Same topicPancreatic function and diabetes→French-language works237,207→