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Record W2474695156 · doi:10.1385/1-59259-321-6:51

General Methods for Culturing Haemophilus influenzae

2003· review· en· W2474695156 on OpenAlexaff
Grant Poje, Rosemary J. Redfield

Bibliographic record

VenueHumana Press eBooks · 2003
Typereview
Languageen
FieldImmunology and Microbiology
TopicBacterial Infections and Vaccines
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsNicotinamide adenine dinucleotideHaemophilus influenzaeNAD+ kinaseHeminMicrobiologyChocolate agarAgarChemistryAgar plateBiochemistryBiologyBacteriaGeneticsEnzymeHemeAntibiotics

Abstract

fetched live from OpenAlex

Haemophilus influenzae is differentiated from other Haemophilus species primarily by its growth requirements for both hemin (called factor X in the old literature) and nicotinamide adenine dinucleotide (NAD or factor V). H. influenzae strains normally grow well in rich media such as brain heart infusion (BHI), suitably supplemented with hemin and NAD (sBHI), and on sBHI or chocolate agar plates. Many isolates classified as H. influenzae differ in their other nutritional requirements, for a purine and for specific amino acids (,). Thus, although a number of defined media have been described, their use often leads to frustration. The medium MMB, described by Klein and Luginbuhl (), is simplest to prepare; when supplemented with a small amount of casamino acids it reproducibly gives good growth.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.019
Threshold uncertainty score0.063

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0050.003
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0030.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0190.058

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.186
GPT teacher head0.426
Teacher spread0.239 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations32
Published2003
Admission routes1
Has abstractyes

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