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ROLE OF MAGNETIC RESONANCE IMAGING IN THE EARLY DIAGNOSIS OF COGNITIVE IMPAIRMENTS IN PATIENTS WITH TYPE 1 DIABETES MELLITUS

2016· article· en· W2476739258 on OpenAlexaboutno aff
М. В. Новоселова, О. С. Тонких

Bibliographic record

VenueDOAJ (DOAJ: Directory of Open Access Journals) · 2016
Typearticle
Languageen
FieldNeuroscience
TopicNeurological Disorders and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMagnetic resonance imagingCognitionType 2 Diabetes MellitusMedicineDiabetes mellitusFunctional magnetic resonance imagingType 1 diabetesNuclear magnetic resonanceRadiologyPsychiatryPhysicsEndocrinology

Abstract

fetched live from OpenAlex

Objective: to assess the role of brain magnetic resonance imaging (MRI) in patients with type 1 diabetes mellitus (DM1) in relation to clinical, metabolic, and psychoneurological disorders.Material and methods. Fifty-eight patients aged 16 to 30 years with DM1 were examined; a control group consisted of 29 healthy young people matched by gender and age. Their examination involved clinical, metabolic, and psychological testing. The quality of life was assessed using the general Medical Outcomes Study Short Form (MOS SF-36) and the specific Audit-Dependent Quality of Life (AdDQoL). The Montreal Cognitive Assessment (MoСа test) was employed to screen for cognitive impairments. All the patients were advised by a neurologist. Brain MRI using a 1.0 T Siemens Magnetom scanner was carried out to evaluate structural changes in the central nervous system.Results. The examination of the patients with DM1 revealed the signs of grey matter atrophy, enlarged Virchow–Robin spaces, white matter injury, which correlated with the presence of chronic hyperglycemia, cognitive impairments, and microvascular complications.Conclusions. Routine brain MRI is best carried out in patients with DM1 and poor disease control to timely implement therapeuticand-prophylactic measures for preventing cognitive impairments and improving the quality of life.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.076
GPT teacher head0.418
Teacher spread0.342 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2016
Admission routes1
Has abstractyes

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