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Record W2485086371 · doi:10.17925/eor.2012.06.02.108

The Light Adjustable Lens – A Review

2012· review· en· W2485086371 on OpenAlexaff
Alejandro Lichtinger

Bibliographic record

VenueEuropean Ophthalmic Review · 2012
Typereview
Languageen
FieldMedicine
TopicIntraocular Surgery and Lenses
Canadian institutionsToronto Western HospitalUniversity of Toronto
Fundersnot available
KeywordsAstigmatismLens (geology)Intraocular lensOpticsRefractive errorOphthalmologyOptometryMedicineMaterials scienceVisual acuityPhysics

Abstract

fetched live from OpenAlex

The purpose of this manuscript is to review the design, development and clinical results of the light adjustable lens (LAL). Evolution in techniques, biometry and intraocular lens (IOL) calculation have improved outcomes and increased expectations after cataract surgery. Nevertheless, Imprecise IOL power determinations, pre-existing and surgical-induced astigmatism, and previous corneal refractive surgery continue to limit post-operative uncorrected vision. The LAL was designed to provide a stable, precise correction of refractive errors with a safe, non-invasive post-operative procedure. The concept behind the LAL is based on photochemistry and diffusion. The adjustment occurs when all non-attached solutes equally distribute themselves throughout the optic after irradiation with ultraviolet light that causes the photosensitive macromers to polymerise in the irradiated region. Clinical results have been positive, with the largest series (122 eyes) showing 97 % of patients within 0.25 D of attempted spherical equivalent and 100 % uncorrected vision 20/25 or better. In conclusion, the LAL has demonstrated to be a safe, accurate and reliable method of post-operative, non-surgical correction of residual sphero-cylindrical refractive error.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.546
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0050.003
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.017

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.110
GPT teacher head0.355
Teacher spread0.245 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2012
Admission routes1
Has abstractyes

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