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Record W2485414950 · doi:10.1145/2908812.2908940

Quantitative Analysis of Evolvability using Vertex Centralities in Phenotype Network

2016· article· en· W2485414950 on OpenAlexaff
Ting Hu, Wolfgang Banzhaf

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEvolution and Genetic Dynamics
Canadian institutionsMemorial University of Newfoundland
Fundersnot available
KeywordsEvolvabilityComputer scienceVertex (graph theory)PhenotypeTheoretical computer scienceEvolutionary biologyBiologyGeneticsGraphGene

Abstract

fetched live from OpenAlex

In an evolutionary system, robustness describes the resilience to mutational and environmental changes, whereas evolvability captures the capability of generating novel and adaptive phenotypes. The research literature has not seen an effective quantification of phenotypic evolvability able to predict the evolutionary potential of the search for novel phenotypes. In this study, we propose to characterize the mutational potential among different phenotypes using the phenotype network, where vertices are phenotypes and edges represent mutational connections between them. In the framework of such a network, we quantitatively analyze the evolvability of phenotypes by exploring a number of vertex centrality measures commonly used in complex networks. In our simulation studies we use a Linear Genetic Programming system and a population of random walkers. Our results suggest that the weighted eigenvector centrality serves as the best estimator of phenotypic evolvability.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.001
Science and technology studies0.0000.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.293
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2016
Admission routes1
Has abstractyes

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