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Record W2494514079 · doi:10.1021/bk-2007-0963.ch020

Kelvin Physics of Protein Layers Printed in Microarray Format

2007· book-chapter· en· W2494514079 on OpenAlex
Hong Huo, Larisa‐Emilia Cheran, Michael Thompson

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueACS symposium series · 2007
Typebook-chapter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced Biosensing Techniques and Applications
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsWork functionKelvin probe force microscopeMaterials scienceProtein adsorptionSaturation (graph theory)ChemistryAdsorptionAnalytical Chemistry (journal)NanotechnologyAtomic force microscopyChromatographyPhysical chemistry

Abstract

fetched live from OpenAlex

The electrical properties of protein molecules adsorbed onto a gold substrate are studied using a scanning Kelvin nanoprobe in a microarray format. The results demonstrate that this instrument can provide information on protein orientation, polarization, dimension and molecular interaction. Changes in the work function for absorbed neutravidin, bovine serum albumin and a complex of the two proteins on gold were measured. Also, the analogous changes with respect to the surface concentration of neutravidin were examined and the results indicate a saturation of work function values at a specific surface population. The results are discussed in terms of the Schottky model modified for protein semiconductive properties, such as depletion width, charge carrier density, band bending and permittivity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.457
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.252
Teacher spread0.239 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it