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Record W2494545381 · doi:10.1007/978-1-61779-597-8_5

Olfactory-Evoked Activity Assay for Larval Zebrafish

2012· book-chapter· en· W2494545381 on OpenAlexafffund
Ganive Bhinder, Keith B. Tierney

Bibliographic record

VenueNeuromethods · 2012
Typebook-chapter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicZebrafish Biomedical Research Applications
Canadian institutionsUniversity of Alberta
FundersCanadian Wildlife Federation
KeywordsZebrafishNeuroscienceOlfactory systemBiologyFish <Actinopterygii>OlfactionLarvaOlfactory receptorOlfactory bulbCentral nervous systemEcologyBiochemistryFisheryGene

Abstract

fetched live from OpenAlex

Olfactory responses develop early in larval zebrafish and are important throughout life to direct physiological and behavioral responses. Responses are evoked by odorants, which act as ligands to the olfactory neuron receptors. A response of immediate relevance is the detection of food odors (i.e., amino acids) which fish have an excellent ability to detect. Characterizing responses of fish to distinct odorants, especially during developmental stages, allows for a robust endpoint to compare to genetically or chemically altered organisms. The following protocol describes the use of automated video analysis to detect changes in olfactory function apparent through a simple behavioral endpoint.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.012
Threshold uncertainty score0.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0120.011

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.066
GPT teacher head0.353
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2012
Admission routes2
Has abstractyes

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