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Record W2497868062 · doi:10.1007/978-1-61779-576-3_39

Electrophysiological Assessment of Cerebral Vasospasm

2012· book-chapter· en· W2497868062 on OpenAlexaff
Jinglu Ai, R. Loch Macdonald

Bibliographic record

VenueSpringer protocols handbooks/Springer protocols · 2012
Typebook-chapter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicIon channel regulation and function
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
Fundersnot available
KeywordsElectrophysiologyVasospasmSubarachnoid hemorrhageNeuroscienceCerebral vasospasmMedicineCardiologyAnesthesiaInternal medicineBiology

Abstract

fetched live from OpenAlex

Cerebral vasospasm is chiefly due to sustained abnormal contraction of smooth muscle cells. Vasospasm develops several days after subarachnoid hemorrhage (SAH) and resolves after 10–14 days. Electrophysiological techniques have been used by several laboratories to elucidate some of the mechanisms involved in experimental vasospasm, including roles of calcium, potassium and transient receptor potential (TRP) channels. The purpose of this chapter is to briefly introduce the instrumentation, materials and procedures for using electrophysiology techniques to study the functional role of ion channels and receptors in smooth muscle cells or potentially other neuronal cells in the brain that may mediate vasospasm and/or brain dysfunction after SAH.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.007
Threshold uncertainty score0.023

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0070.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.315
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2012
Admission routes1
Has abstractyes

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Same venueSpringer protocols handbooks/Springer protocolsSame topicIon channel regulation and functionFrench-language works237,207