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Record W2503101510 · doi:10.1007/978-1-60327-202-5_1

Field Potential Generation and Current Source Density Analysis

2010· book-chapter· en· W2503101510 on OpenAlexaff
L. Stan Leung

Bibliographic record

VenueNeuromethods · 2010
Typebook-chapter
Languageen
FieldNeuroscience
TopicNeural dynamics and brain function
Canadian institutionsWestern University
Fundersnot available
KeywordsCurrent sourceExcitationPhysicsField (mathematics)Current (fluid)PopulationLocal field potentialNeuroscienceMathematicsBiology

Abstract

fetched live from OpenAlex

The basic principles underlying field potential generation and the application of current source density (CSD) analysis are outlined in this chapter. Currents in the brain are mainly derived from synaptic or action currents flowing in a closed loop, traversing both intracellular and extracellular media. Extracellular currents generate the field potentials, with a spatial organization of an open or a closed field that may be standing or traveling. CSD analysis is the method used to derive the macroscopic sources and sinks that generate a potential field. Assuming that the medium is homogeneous and resistive, CSD can be approximated by a second-order derivative of the field potential. When the activation is spatially extensive, the current may essentially flow in one or two dimensions, and the CSD may be approximated using one- or two-dimensional mapping. The field potentials should first be mapped regularly at an adequate interval, over an appropriate spatial extent. A multichannel electrode array offers accurate sampling intervals, and the field potentials can be sampled simultaneously in one or two dimensions. Examples of potential fields and CSDs in a layered cortical structure (hippocampal CA1 area) are illustrated, with different fields generated by basal or apical dendritic excitation, proximal and distal dendritic excitation, proximal inhibition, and synchronous action potentials (population spikes). Generation of field potentials from sinks and sources of neuronal cables, arranged in a particular geometry, may be used to predict the CSD profiles. Successful application of CSD analysis would facilitate the understanding of neuronal dynamics, synaptic transmission, and plasticity in cortical structures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.606
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.053
GPT teacher head0.304
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations14
Published2010
Admission routes1
Has abstractyes

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