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Record W2503156707 · doi:10.3201/eid2209.160177

<i>mcr-1</i>–Positive Colistin-Resistant<i>Escherichia coli</i>in Traveler Returning to Canada from China

2016· letter· en· W2503156707 on OpenAlexafffundabout
Michael Payne, Matthew A. Croxen, Tracy D. Lee, Brian Mayson, Sylvie Champagne, Vyl Leung, Sherri Bariso, Linda Hoang, Christopher J. Lowe

Bibliographic record

VenueEmerging infectious diseases · 2016
Typeletter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAntibiotic Resistance in Bacteria
Canadian institutionsUniversity of British ColumbiaBC Centre for Disease ControlProvidence Health Care
FundersBritish Columbia Centre for Disease ControlProvidence Health CarePublic Health AgencyPublic Health Agency of Canada
KeywordsMCR-1ColistinEscherichia coli ProteinsEscherichia coliChinaMicrobiologyEnterobacteriaceae InfectionsTraveler's diarrheaMedicineBiologyEnvironmental healthGeographyAntibioticsEnterobacteriaceaeGeneticsInternal medicineGeneDiarrhea

Abstract

fetched live from OpenAlex

To the Editor: A 61-year-old man underwent transurethral prostate resection in Vancouver, British Columbia, in January 2016. On postoperative day 1, he was febrile (39.1°C) and had leukocytosis (12.7 × 109 cells/L). Blood and urine cultures were ordered on postoperative day 2, and ceftriaxone was started. On postoperative day 3, urine culture grew Escherichia coli (>100 million CFU/L). Susceptibility testing (VITEK2, bioMerieux, Quebec, Canada) indicated a possible extended-spectrum β-lactamase producer and showed resistance to ampicillin, cefazolin, ceftriaxone, gentamicin, ciprofloxacin, and trimethoprim/sulfamethoxazole; intermediate resistance to tobramycin; and susceptibility to amoxicillin/clavulanate, piperacillin/tazobactam, ertapenem, meropenem, and nitrofurantoin. Treatment was switched to amoxicillin/clavulanate. The urinary catheter was removed 48 hours later. The patient was discharged on postoperative day 5 and completed 14 days of oral amoxicillin/clavulanate. Blood cultures were negative after 7 days’ incubation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.211
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.214
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations45
Published2016
Admission routes3
Has abstractyes

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